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Cover
Document and Entity Information
Financial Statements
Consolidated Balance Sheets
Consolidated Balance Sheets (Parenthetical)
Consolidated Statements of Operations and Other Comprehensive Loss
Consolidated Statements of Stockholders' Equity
Consolidated Statements of Cash Flows
Notes to Financial Statements
Description of Business and Summary of Significant Accounting Policies
Fixed Assets
Accrued Expenses
Collaborative Research, Development, and License Agreements
Stockholders' Equity
Leases
Commitments and Contingencies
Income Taxes
Concentrations
Related Parties
Defined Contribution Plan
Recent Accounting Pronouncements
Restructuring
Subsequent Events
Accounting Policies
Description of Business and Summary of Significant Accounting Policies (Policies)
Recent Accounting Pronouncements (Policies)
Notes Tables
Fixed Assets (Tables)
Accrued Expenses (Tables)
Collaborative Research, Development, and License Agreements (Tables)
Stockholders' Equity (Tables)
Leases (Tables)
Income Taxes (Tables)
Restructuring (Tables)
Notes Details
Description of Business and Summary of Significant Accounting Policies - Additional Information (Detail)
Fixed Assets - Schedule of Fixed Assets (Detail)
Fixed Assets - Additional Information (Detail)
Fixed Assets - Summary of Assets Held for Sale (Detail)
Accrued Expenses - Summary of Accrued Expenses (Detail)
Collaborative Research, Development, and License Agreements - Additional Information (Detail)
Collaborative Research, Development, and License Agreements - Schedule of Capitalized License Fees (Detail)
Stockholders' Equity - Schedule of Stock-based Compensation Expense (Detail)
Stockholders' Equity - Stock-based Compensation Expense and Valuation Information - Additional Information (Detail)
Stockholders' Equity - Fair Value of Employee Stock Options (Detail)
Stockholders' Equity - Fair Value of Employee Stock Purchase Plan (Detail)
Stockholders' Equity - Fair Value of Employee Stock Purchase Plan (Parenthetical) (Detail)
Stockholders' Equity - Preferred Stock - Additional Information (Detail)
Stockholders' Equity - Common Stock - Additional Information (Detail)
Stockholders' Equity - Restricted Stock Units and Performance-Based Restricted Stock Units - Additional Information (Detail)
Stockholders' Equity - Summary of Company's Restricted Stock Unit Activity and Performance Based Restricted Stock Unit Activity (Detail)
Stockholders' Equity - Restricted Stock Awards, Restricted Stock Units and Performance-Based Restricted Stock Units - Additional Information (Detail)
Stockholders' Equity - Stock Options and Employee Stock Purchase Plan - Additional Information (Detail)
Stockholders' Equity - Summary of Stock Option Activity (Detail)
Stockholders' Equity - Summary of Warrant Activity (Detail)
Stockholders' Equity - Warrants - Additional Information (Detail)
Stockholders' Equity - Common Stock Reserved for Future Issuance (Detail)
Leases - Additional Information (Details)
Leases - Schedule of Impact of Adoption of ASC 842 on Consolidated Balance Sheet (Details)
Leases - Summary of Cash Flows Associated with Company's Leases (Details)
Income Taxes - Summary of Reconciliation of Statutory Federal Rate and Effective Rate for Operations (Detail)
Income Taxes - Summary of Net Deferred Tax Assets (Detail)
Income Taxes - Additional Information (Detail)
Related Parties - Additional Information (Detail)
Defined Contribution Plan - Additional Information (Details)
Restructuring - Additional Information (Details)
Restructuring - Summary of Restructuring Charges Recorded in Selling, General and Administrative Expenses (Details)
Restructuring - Summary of Activity and Balances of Restructuring Reserve (Details)
Subsequent Events - Additional Information (Detail)
All Reports